| 产品详情 |
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| Product Name | MK-0974 |
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| Description | A CGRP receptor antagonist (Ki = 0.77 µM); binds selectively to the human CGRP receptor complex over the adrenomedullin receptor complexes in HEK293 cells (Kis = >100 and 29 µM for CRLR with RAMP2 and 3, respectively); inhibits CGRP-induced cAMP accumulation in HEK293 cells expressing the CGRP receptor complex (IC50 = 2.2 nM); reduces CGRP-induced vasodilation in isolated human meningeal arteries; inhibits vasodilation induced by topical application of capsaicin in rhesus monkeys (EC50 = 127 nM) |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MK0974 telcagepant RAMP-1 2 3 HEK-293 |
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| Gene, Accession, CAS # | CAS: 781649-09-0 |
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| Catalog # | 23960-10 |
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| Price | |
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| Order / More Info | MK-0974 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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