产品详情 |
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Antigenic Specificity | RCA60 |
Clone | CP75 |
Host Species | Mouse |
Reactive Species | plant |
Isotype | IgG1 |
Format | purified |
Size | 500 µg |
Concentration | n/a |
Applications | ELISA: Assay-dependent, Western Blot: Assay dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RCA60 Monoclonal Antibody (CP75). Ricinus communis agglutinin 60 is a heterodimeric glycoprotein consisting of an A chain (RTA, ricin toxin A chain) disulphide-linked to a B chain (RTB, ricin toxin B chain). RTA is an N glycosidase, responsible for ricin cytotoxicity, that depurinates adenine residue 4324 of the 28S rRNA, thus inactivating protein synthesis. Since its endocytotic properties are very limited, RTA alone shows a very low level of cytotoxicity. RTB is a galactose specific lectin containing three galactose-binding sites. Mutation or deletion of any one of these sites reduces the ability of ricin to penetrate into the cell. |
Immunogen | n/a |
Other Names | Ricinus communis agglutinin 60 |
Gene, Accession # | n/a |
Catalog # | MA1-91115 |
Price | |
Order / More Info | RCA60 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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