产品详情 |
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Antigenic Specificity | HSF2 |
Clone | OTI2A7 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HSF2 Monoclonal Antibody (OTI2A7). Prokaryotic and eukaryotic cells respond to thermal and chemical stress by inducing a group of genes collectively designated heat shock genes. In eukaryotes, this gene expression is regulated primarily at the transcription level. Heat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation. HSF1 and HSF2 are upregulated by estrogen at both the mRNA and protein level. HSF1 is normally found as a monomer whose transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus. HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA |
Immunogen | n/a |
Other Names | Heat shock factor protein 2; HSF 2; Heat shock transcription factor 2; HSTF 2; HSTF2 |
Gene, Accession # | Entrez: 3298; Uniprot: Q03933 |
Catalog # | MA5-26871 |
Price | |
Order / More Info | HSF2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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