| 产品详情 |
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| Antigenic Specificity | HSF1 |
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| Clone | 4B4 |
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| Host Species | Rat |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Gel Shift: 1mg/mL, Immunofluorescence: Assay Dependent, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HSF1 Monoclonal Antibody (4B4). HSF1 responds to cellular stress signals such as heat, heavy metals, and oxidative reagents; binds to heat shock response elements (HSEs) in the upstream region of heat shock gene and activates their transcription. Some laboratories have reported that the constitutive, non-DNA binding, monomeric form of inactive HSF1 is located in the cytoplasm. Upon activation, HSF1 is trimerized and is localized in nucleus where it binds DNA. |
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| Immunogen | n/a |
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| Other Names | HSF 1; HSTF 1; heat shock factor protein 1 |
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| Gene, Accession # | Entrez: 15499, 3297, 79245; Uniprot: P38532, Q00613 |
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| Catalog # | MA5-14622 |
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| Price | |
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| Order / More Info | HSF1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11585899, 12058070, 18039709, 18059335, 18457423, 25404049 |
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