Edit |   |
Antigenic Specificity | Sprouty 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 10 µL |
Concentration | n/a |
Applications | Immunoprecipitation: 2-10 µg/mg lysate |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Sprouty 2 Polyclonal Antibody. This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mi |
Immunogen | n/a |
Other Names | Sprouty homolog 2 (Drosophila), MGC23039, hSPRY2 |
Gene, Accession # | Entrez: 10253; Uniprot: O43597 |
Catalog # | A303-535A-T |
Price | |
Order / More Info | Sprouty 2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |