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Product Name | Milbemycin A4 oxime |
Description | A derivative of milbemycin A4 and a component of milbemycin oxime; reduces the number of microfilariae of the heartworm D. immitis in naturally infested dogs at 0.05 mg/kg; inhibits the growth of clinical isolates of C. glabrata (MIC80s = 16 to >32 µg/ml); blocks efflux of fluconazole from a clinical isolate of C. glabrata, but not from a strain lacking the efflux pumps CgCDR1 and PDH1, at 2.5 µg/ml; reduces the MICs of fluconazole and 4-nitroquinoline 1-oxide in wild-type C. glabrata; enhances adriamycin-induced inhibition of cell growth in adriamycin-resistant, but not -sensitive, MCF-7 breast cancer cells; increases the intracellular accumulation of adriamycin and rhodamine 123 in adriamycin-resistant, but not -sensitive, MCF-7 breast cancer cells |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-oxomilbemycin A4 5-oxime |
Gene, Accession, CAS # | CAS: 93074-04-5 |
Catalog # | 27938-1 |
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Order / More Info | Milbemycin A4 oxime from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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