| 产品详情 |
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| Product Name | GSK-J4 (hydrochloride) |
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| Description | An ethyl ester prodrug of the JMJD3 selective histone demethylase inhibitor GSK-J1; reduces LPS-induced proinflammatory cytokine production, including that of TNFα (IC50 = 9 µM) in human primary macrophages |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1373423-53-0 epigenetics demethylase histones JMJD3 cells differentiation developments inflammation cancers GSK-J1 pro-drug prodrugs H3 lysine 27 H3K27 H3K-27 GSKJ1 GSKs J1 GSKJ4 J4 inhibitors inhibits inhibitions macrophages reduce LPS induce induced proinflammatory inflammatory pro pro-inflammatory cytokines TNF.alpha. TNF-.alpha. TNF .alpha. TNF-alpha TNF-a TNF-α TNFalpha TNFa TNFα alpha α HCl Structural Genomic Consortium SGC |
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| Gene, Accession, CAS # | CAS: 1797983-09-5 |
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| Catalog # | 12073-1 |
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| Order / More Info | GSK-J4 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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