产品详情 |
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Antigenic Specificity | GPR68 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 1-2 µg/mL, Immunofluorescence: 1-2 µg/mL, Immunohistochemistry: 2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GPR68 Polyclonal Antibody. GPR68 (also known as OGR1) is a high-affinity receptor for sphingosylphosphorylcholine (SPC). SPC is a member of a class of bioactive lipids which regulate cellular functions. These functions include cell proliferation and growth inhibition, smooth muscle contraction and wound healing. SPC also stimulated signaling pathways that induce tyrosine phosphorylation, activate MAP kinases and protein kinase C, modify ion channel activity and increase intracellular Ca2+ concentration. GPR68 is expressed in placenta, lung, liver, spleen, testis, small intestine and peripheral blood leukocytes. It is not found in thymus, ovary, colon, skeletal muscle, kidney or pancreas. Found to serve as a tumor suppressor in prostate canc |
Immunogen | n/a |
Other Names | G Protein-Coupled Receptor 37 |
Gene, Accession # | Entrez: 8111; Uniprot: Q15743 |
Catalog # | 720359 |
Price | |
Order / More Info | GPR68 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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