| 产品详情 |
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| Antigenic Specificity | DR1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This gene encodes a TBP (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. This DR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-112 amino acids from the Central region of human DR1. |
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| Immunogen | Human DR1. |
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| Other Names | down-regulator of transcription 1; TBP-binding (negative cofactor 2); DR1; NC2; NC2-BETA; Protein Dr1; Negative cofactor 2-beta; TATA-binding protein-associated phosphoprotein |
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| Gene, Accession # | SwissProt: Q01658 |
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| Catalog # | abx029804 |
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| Price | |
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| Order / More Info | DR1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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| 产品资料 |
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