产品详情 |
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Antigenic Specificity | CD45 |
Clone | 30-F11 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b, kappa |
Format | allophycocyanin (APC) conjugate |
Size | 200 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.125 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45 Monoclonal Antibody (30-F11), APC, eBioscience™. CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains. CD45RA is an isoform of the CD45 complex and has restricted ex |
Immunogen | n/a |
Other Names | Cluster designation 45, common leukocyte antigen, T220 and B220 |
Gene, Accession # | Entrez: 19264; Uniprot: P06800 |
Catalog # | 17-0451-83 |
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Order / More Info | CD45 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 15833919, 16611687, 17526859, 18975389, 19574419, 21159661, 21169470, 21296664, 21421850, 21680798, 21703864, 21937694, 21989919, 22186994, 22287719, 22340596, 22377050, 22522620, 22628281, 22686371, 22871668, 23077247, 23178246, 23376424, 23484127, 23529619, 23831688, 23894196, 23954132, 24025738, 24366868, 24382123, 24401681, 24446236, 24532804, 24624965, 24733756, 24830425, 24892809, 24905997, 24936469, 25031461, 25143871, 25156732, 25445147, 25451154, 25569216, 25658639, 25664855, 25693182, 25722188, 25858253, 25862076, 25870111, 26030851, 26047815, 26107883, 26170908, 26257993, 26277898, 26344905, 26347471, 26399548, 26452100, 26466563, 26572749, 26573799, 26617239, 26627131, 26656646, 26779981, 26854397, 26865503, 26944199, 26950855, 27057467, 27068235, 27068890, 27310015, 27335895, 27525437, 27538380, 27577867, 27581448, 27659202, 27860312, 27869129, 27976999, 28000790, 28134623, 28188247, 28218906, 28240601, 28273719, 28332979, 28485322, 28494939, 28594896, 28716934, 28814662, 28839138, 28875933, 28973433, 29162901, 29187227, 29296022, 29500407, 29670099 |
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