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Antigenic Specificity | CD45 |
Clone | 30-F11 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b, kappa |
Format | purified |
Size | 500 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45 Monoclonal Antibody (30-F11), eBioscience™. CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains. CD45RA is an isoform of the CD45 complex and has restricted express |
Immunogen | n/a |
Other Names | Cluster designation 45, common leukocyte antigen, T220 and B220 |
Gene, Accession # | Entrez: 19264; Uniprot: P06800 |
Catalog # | 14-0451-85 |
Price | |
Order / More Info | CD45 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 16938836, 17702899, 17897956, 18464929, 18558197, 19020532, 19085956, 19360122, 19574419, 19864606, 20404100, 21056990, 21178002, 21340652, 21365015, 21514665, 21525884, 21633411, 21703864, 21714479, 21825019, 21989919, 22005300, 22222225, 22363815, 22425250, 22440612, 22464170, 22472773, 22628281, 22686371, 22729249, 22820644, 22844125, 22990625, 22993390, 23036899, 23066023, 23211619, 23267022, 23284862, 23319699, 23348743, 23370675, 23414756, 23434824, 23562810, 23585844, 23615497, 23624557, 23650399, 23671208, 23704211, 23748430, 23980105, 24012753, 24106006, 24166977, 24222670, 24324557, 24366868, 24396708, 24399752, 24401681, 24412613, 24446236, 24566711, 24583793, 24624965, 24633226, 24683512, 24733756, 24766345, 24807637, 24829059, 24913979, 24937432, 24968718, 24991401, 25037571, 25074920, 25100292, 25142145, 25238161, 25332287, 25347065, 25445147, 25492473, 25559893, 25563499, 25568183, 25575242, 25591994, 25658639, 25664855, 25693182, 25710908, 25710911, 25769612, 25807527, 25857745, 25858253, 26026061, 26030851, 26047815, 26071560, 26107883, 26129648, 26136374, 26147083, 26151762, 26170908, 26241678, 26242598, 26242630, 26252890, 26257993, 26277898, 26344905, 26347713, 26408258, 26424146, 26472817, 26572749, 26601958, 26617239, 26645581, 26656646, 26663781, 26694097, 26699479, 26779981, 26789017, 26789196, 26802627, 26829557, 26854397, 26876212, 27043409, 27057467, 27068890, 27165837, 27183387, 27195312, 27220367, 27335895, 27441847, 27479084, 27538380, 27577867, 27659202, 27699223, 27853644, 27860312, 27912060, 27926943, 28000790, 28094767, 28134623, 28165063, 28218906, 28273719, 28332979, 28485322, 28494939, 28594896, 28716934, 28814662, 29098081, 29162901, 29187227, 29500407 |
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