产品详情 |
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Antigenic Specificity | CD45 |
Clone | 1.11.32 |
Host Species | Mouse |
Reactive Species | sheep |
Isotype | IgG1 |
Format | biotin conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: Assay-dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45 Monoclonal Antibody (1.11.32), Biotin. CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains. CD45RA is an isoform of the CD45 complex and has restricted expression between |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 101102917 |
Catalog # | MA5-28380 |
Price | |
Order / More Info | CD45 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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