| 产品详情 |
| Edit |   |
|---|
| Product Name | CAY10471 |
|---|
| Description | The biological effects of PGD2 are transduced by at least two 7-transmembrane G-protein coupled receptors, designated DP1 and CRTH2/DP2. BAY-u3405 (Ramatroban) is an approved human medication for the treatment of allergic rhinitis that has documented activity as an antagonist of both the TP and CRTH2/DP2 receptors.{11248,12335} CAY10471 is an analog of BAY-u3405 which contains modifications that increase both its potency and selectivity for the human CRTH2/DP2 receptor.{12777} CAY10471 binds to the human CRTH2/DP2, DP1, and TP receptors with Ki values of 0.6, 1200, and >10,000 nM, respectively.{12777} |
|---|
| Size | 50 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | TM30089 |
|---|
| Gene, Accession, CAS # | CAS: 627865-18-3 |
|---|
| Catalog # | 10006735-50 |
|---|
| Price | |
|---|
| Order / More Info | CAY10471 from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|