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| Product Name | CAY10471 |
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| Description | The biological effects of PGD2 are transduced by at least two 7-transmembrane G-protein coupled receptors, designated DP1 and CRTH2/DP2. BAY-u3405 (Ramatroban) is an approved human medication for the treatment of allergic rhinitis that has documented activity as an antagonist of both the TP and CRTH2/DP2 receptors.{11248,12335} CAY10471 is an analog of BAY-u3405 which contains modifications that increase both its potency and selectivity for the human CRTH2/DP2 receptor.{12777} CAY10471 binds to the human CRTH2/DP2, DP1, and TP receptors with Ki values of 0.6, 1200, and >10,000 nM, respectively.{12777} |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TM30089 |
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| Gene, Accession, CAS # | CAS: 627865-18-3 |
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| Catalog # | 10006735-5 |
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| Order / More Info | CAY10471 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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