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| Antigenic Specificity | CASC5 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 10 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-5 µg/mg lysate |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CASC5 Polyclonal Antibody. Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Required for attachment of the kinetochores to the spindle microtubules. Directly links BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore. |
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| Immunogen | n/a |
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| Other Names | Protein CASC5, Cancer susceptibility candidate gene 5 protein homolog, Kinetochore-null protein 1, Casc5, Knl1 |
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| Gene, Accession # | Entrez: 57082; Uniprot: Q8NG31 |
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| Catalog # | A300-804A-T |
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| Price | |
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| Order / More Info | CASC5 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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