| 产品详情 |
| Edit |   |
|---|
| Product Name | Mifepristone |
|---|
| Description | An antagonist of glucocorticoid, progesterone, and androgen receptors (Kis = 0.1, 0.64, and 0.65 nM, respectively); selective for these receptors over MR, ERα, and ERβ (Kis = 640, >200, and >750 nM, respectively); inhibits R5020-stimulated alkaline phosphatase activity as well as reporter transcription stimulated by either dexamethasone or R5020 in cell-based assays (IC50s = 7, 5.9, and 1.3 nM, respectively); inhibits R1881-stimulated reporter transcription in a concentration-dependent manner; inhibits growth of 4-OHT-resistant MCF-7 breast cancer cells in vitro at 10 µM; inhibits tumor growth in an SKOV3 ovarian cancer nude mouse xenograft model at 0.5 or 1 mg per day |
|---|
| Size | 500 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | RU-486 |
|---|
| Gene, Accession, CAS # | CAS: 84371-65-3 |
|---|
| Catalog # | 10006317-500 |
|---|
| Price | |
|---|
| Order / More Info | Mifepristone from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|