| 产品详情 |
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| Product Name | PF-4708671 |
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| Description | PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with a Ki of 20 nM and IC50 of 160 nM. PF-4708671 prevents the S6K1-mediated phosphorylation of S6 protein in response to IGF-1 (insulin-like growth factor 1), while having no effect upon the PMA-induced phosphorylation of substrates of the highly related RSK (p90 ribosomal S6 kinase) and MSK (mitogen- and stress-activated kinase) kinases. MW: 390.41. Purity ≥98% by HPLC |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzo[d]imidazole |
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| Gene, Accession, CAS # | CAS: 1255517-76-0 |
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| Catalog # | 9460-10 |
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| Order / More Info | PF-4708671 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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