| 产品详情 |
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| Product Name | PF-06840003 |
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| Description | PF-06840003 is a highly selective orally bioavailable indoleamine 2,3-dioxygenase -1 (IDO-1) inhibitor (IC50 = 0.15 µM for human enzyme). It inhibits IDO-1-mediated production of kynurenine induced by IFN-γ in HeLa cells (IC50 = 1.8 µM) and by LPS and IFN-γ in THP-1 cells and human-derived whole blood ex vivo (IC50s = 1.7 and 4.7 µM, respectively). MW: 232.21. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3?(5-Fluoro?1H?indol-3-yl)pyrrolidine-2,5-dione; EOS 200271 |
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| Gene, Accession, CAS # | CAS: 198474-05-4 |
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| Catalog # | B2218-5 |
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| Order / More Info | PF-06840003 from BIOVISION, INC. |
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| Product Specific References | n/a |
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