| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | KSHV ORF45 |
|---|
| Clone | 2D4A5 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | n/a |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry: 1/200 - 1/1000, Western Blot: 1/500 - 1/2000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | KSHV ORF45 Monoclonal Antibody (2D4A5). Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. ORF45 protein encoded by an immediate-early gene in the KSHV genome is characterized as a phosphorylated protein, and it is localized in the cytoplasm of infected cells. Studies have shown that ORF45 Protein interacted with cellular IRF-7 and blocked virus-mediated phosphorylation and nuclear translocation of IRF-7. In consequence, ORF45 efficiently inhibited virus-induced production of type I IFN. Zhu et al (2 |
|---|
| Immunogen | n/a |
|---|
| Other Names | Kaposi's sarcoma-associated herpesvirus |
|---|
| Gene, Accession # | n/a |
|---|
| Catalog # | MA5-14769 |
|---|
| Price | |
|---|
| Order / More Info | KSHV ORF45 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 28459883 |
|---|
| 产品资料 |
|
|