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| Product Name | 11-trans Leukotriene C4 |
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| Description | 11-trans LTC4 is a C-11 double bond isomer of LTC4. LTC4 undergoes slow temperature-dependent isomerization to 11-trans LTC4 during storage. 11-trans LTC4 is produced in smaller amounts relative to LTC4 in ionophore-stimulated HMC-1 cells (a human mast cell line) and equine eosinophils{11135}, but not in human neutrophils or RBL-1 cells.{11184} It is nearly equipotent with LTC4 for contraction of guinea pig parenchymal and ileum.{2070,11187} In a radioligand binding assay using guinea pig ileum as a cysteinyl leukotriene receptor preparation, the pKis for LTC4 and 11-trans LTC4 were determined to be 6.42 and 6.58, respectively.{11187} |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 11-trans LTC4 |
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| Gene, Accession, CAS # | CAS: 74841-69-3 |
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| Catalog # | 20230-50 |
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| Order / More Info | 11-trans Leukotriene C4 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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