产品详情 |
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Antigenic Specificity | SPARC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 70 µg |
Concentration | n/a |
Applications | ELISA: Assay Dependent, Immunohistochemistry: Assay Dependent, Western Blot: 0.5-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SPARC Polyclonal Antibody. SPARC is a key factor in cell-matrix interactions and possibly tumour aggressiveness. The SPARC gene, which encodes a multifunctional glycoprotein with roles in tissue development, remodelling and fibrosis. A regulator of cell-extracellular matrix (ECM) interactions, SPARC represents a major factor in the ECM remodelling occurring during tumour invasion. in silico analysis reveals 4 UTR-SNPs located in the 3'-UTR of the SPARC gene, corresponding to 1474 g a, 1551 g c, 1922 t g and 2072 c t changes, which are significantly associated with tumoral state of the tissue. Of all hits, the 2072 SPARC polymorphism had the best association with cancer. SPARC therefore is a gene involved in a number of diseases including rh |
Immunogen | n/a |
Other Names | ON |
Gene, Accession # | Entrez: 6678; Uniprot: P09486 |
Catalog # | PA1-12865 |
Price | |
Order / More Info | SPARC Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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