| 产品详情 |
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| Product Name | Pranlukast |
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| Description | Pranlukast (ONO-1078) is a potent, selective and orally active CysLT1 receptor antagonist.{14104} Sold under the trade name Ultair, it was the first cysteinyl (peptidyl) leukotriene receptor antagonist (LTRA) marketed for the treatment of asthma.{14103} Clinical studies in Japan, Europe, and North America all show that pranlukast significantly attenuates bronchoconstriction in response to a variety of allergen challenges as well as to inhaled LTD4.{14103} Pranlukast binds to the human CysLT1 and CysLT2 receptors with IC50 values of approximately 4-7 nM and 3,600 nM, respectively.{7174,8519,14081} |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ONO-1078|Ultair |
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| Gene, Accession, CAS # | CAS: 103177-37-3 |
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| Catalog # | 10008319-10 |
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| Order / More Info | Pranlukast from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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