产品详情 |
Edit |   |
Product Name | Nemorosone |
Description | An PPAP with antiproliferative properties; inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma cells (IC50s = 3.1-6.3 µM); inhibits growth of Capan-1, AsPC-1, and MIA-PaCa-2 pancreatic cancer cells (IC50s = 4.5-5.0 µM, 72-hour treatment); activates the caspase cascade in a dose-dependent manner and inhibits cell cycle progression, increasing the proportion of cells in G0/G1 phase, in both neuroblastoma and pancreatic cancer cells; reduces tumor growth in an MIA-PaCa-2 mouse xenograft model (50 mg/kg, i.p., per day) |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 182250-24-4 Memorosone Clonostachys NB-69 SKNAS LAN1 MRC5 anti-proliferative NMyc ERK-1 2 MEK-1 2 AsPC1 MIAPaCa2 |
Gene, Accession, CAS # | CAS: 351416-47-2 |
Catalog # | 24256-5 |
Price | |
Order / More Info | Nemorosone from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
产品资料 |
|
|