| 产品详情 |
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| Product Name | Bosutinib |
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| Description | An inhibitor of c-Src and Abl kinases (IC50s = 1.2 and 1 nM, respectively); inhibits the kinases EPHB2, TrkA, TrkB, and TXK (IC50s = 8.5, 22, 27, and 40 nM, respectively) among others; inhibits Src-dependent cell proliferation (IC50 = 100 nM); reduces tumor growth in unstaged and staged Src-transformed fibroblast mouse xenograft models at 30 or 25 mg/kg, respectively, twice per day; induces complete tumor regression in a K562 mouse xenograft model at 100 mg/kg once per day for five days |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SKI 606 |
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| Gene, Accession, CAS # | CAS: 380843-75-4 |
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| Catalog # | 12030-10 |
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| Price | |
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| Order / More Info | Bosutinib from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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