产品详情 |
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Antigenic Specificity | CCDC106 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 5 µg/mL, Western Blot: 0.5-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CCDC106 Polyclonal Antibody. The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53. |
Immunogen | n/a |
Other Names | HSU79303, ZNF581; coiled-coil domain-containing protein 106; protein predicted by clone 23882 |
Gene, Accession # | Entrez: 232821, 29903, 499071; Uniprot: Q3ULM0, Q9BWC9 |
Catalog # | PA5-21003 |
Price | |
Order / More Info | CCDC106 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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