产品详情 |
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Product Name | Etelcalcetide |
Description | A peptide agonist of CaSR; selective for CaSR over a panel of 33 receptors and ion channels, as well as the norepinephrine transporter at 10 µM; increases intracellular calcium levels in HEK293T cells expressing the human CaSR receptor (EC50 = 0.53 µM); inhibits parathyroid secretion from primary rat parathyroid cells (EC50 = 0.36 µM in the presence of calcium); decreases parathyroid hormone and calcium in plasma and serum, respectively, in a model of chronic renal insufficiency with secondary hyperthyroidism in nephrectomized rats fed high-phosphorus diet at 0.3, 1, and 3 mg/kg |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | AMG 416|KAI 4169|Velcalcetide |
Gene, Accession, CAS # | CAS: 1262780-97-1 |
Catalog # | 26901-10 |
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Order / More Info | Etelcalcetide from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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