| 产品详情 |
| Edit |   |
| Antigenic Specificity | AMPK alpha 1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | purified |
| Size | 80 µl, 400 µl |
| Concentration | n/a |
| Applications | WB. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. It appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. AMPK alpha1, a member of the Ser/Thr protein kinase family, is a catalytic subunit of AMPK. This AMPK alpha 1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 479-510 amino acids from the C-terminal region of human AMPK alpha 1. |
| Immunogen | Human AMPK alpha 1. |
| Other Names | AMPK alpha 1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1; PRKAA1 |
| Gene, Accession # | SwissProt: Q13131 |
| Catalog # | abx033226 |
| Price | |
| Order / More Info | AMPK alpha 1 Antibody from ABBEXA |
| Product Specific References | n/a |
| 产品资料 |
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