| 产品详情 |
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| Antigenic Specificity | Tryptophan Hydroxylase |
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| Clone | polyclonal |
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| Host Species | Sheep |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Frozen): 1:1000, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Tryptophan Hydroxylase Polyclonal Antibody. Tryptophan hydroxylase (TPH) catalyzes the first step in the biosynthesis of serotonin and melatonin (Martinez et al., 2001). Thus expression of TPH can be used as an indicator of the localization of serotonin and melatonin in brain. In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland (Haycock et al., 2002) . Although TPH catalyzes the same reaction within the Raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis (Martinez et al., 2001). |
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| Immunogen | n/a |
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| Other Names | TPH, TPH1, TPRH, Tryptophan 5 hydroxylase 1, Tryptophan 5 monooxygenase 1, Tryptophan hydroxylase 1 |
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| Gene, Accession # | Entrez: 24848, 7166; Uniprot: P09810, P17752 |
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| Catalog # | PA1-4678 |
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| Price | |
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| Order / More Info | Tryptophan Hydroxylase Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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