| 产品详情 |
| Edit |   |
|---|
| Product Name | CP 690,550 |
|---|
| Description | A JAX inhibitor (IC50s = 6.1, 12, and 8 nM for JAK1, JAK2, and JAK3, respectively); selective for JAK1-3 over ROCK-II and Lck (IC50s = 3,400 and 3,870 nM, respectively) as well as 28 additional kinases in enzyme assays (IC50s = >10,000 nM); inhibits IL-2-mediated phosphorylation of JAK3 and STAT5 (30 ng/ml); prevents rejection and prolongs survival in murine and cynomolgus monkey models of heterotopic heart and kidney transplantation |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Tofacitinib citrate |
|---|
| Gene, Accession, CAS # | CAS: 540737-29-9 |
|---|
| Catalog # | 11598-10 |
|---|
| Price | |
|---|
| Order / More Info | CP 690,550 from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|