| Edit |   |
| Antigenic Specificity | PLEKHF1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl |
| Concentration | n/a |
| Applications | WB. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PLEKHF1 may induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8. This PLEKHF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human PLEKHF1. |
| Immunogen | Human PLEKHF1. |
| Other Names | APPD; LAPF; PHAFIN1; ZFYVE15; pleckstrin homology domain containing; family F (with FYVE domain) member 1; PLEKHF1; MGC4090; Pleckstrin homology domain-containing family F member 1; Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains; PH and FYVE domain-containing protein 1; Phafin-1; Zinc finger FYVE domain-containing protein 15 |
| Gene, Accession # | PLEKHF1, SwissProt: Q96S99 |
| Catalog # | abx028879 |
| Price | |
| Order / More Info | PLEKHF1 Antibody from ABBEXA |
| Product Specific References | n/a |