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| Product Name | 11-deoxy Prostaglandin E1 |
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| Description | 11-deoxy PGE1 is a synthetic analog of PGE1. Early reports show that it is a selective agonist for the EP2 receptor but effective at much higher concentrations than PGE2.{1360,1026} However, later studies show that it is a non-selective agonist of EP receptors and stimulates cAMP release in Jurkat cells with an EC50 of 0.25 µM.{2120} 11-deoxy PGE1 also exhibits vasodepressor and bronchodilator responses in guinea pigs.{2217} 11-deoxy PGE1 exhibits selectively for the mouse EP3 receptor and is essentially equipotent to PGE1 at this receptor subtype. The Ki values for binding to the murine EP1, EP2, EP3, and EP4 receptors are 600, 45, 1.1, and 23 nM, respectively.{6640} |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 11-deoxy PGE1 |
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| Gene, Accession, CAS # | CAS: 37786-00-8 |
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| Catalog # | 13510-5 |
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| Order / More Info | 11-deoxy Prostaglandin E1 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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