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Product Name | PGPC |
Description | Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes and activate PMNL.{8499} Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position.{9891} One of these substances An oxidized phospholipid found as a component in MM-LDL and in products of Ox-PAPC; activates PPARα in a concentration-dependent manner; increases VCAM1 and E-selectin expression in HAECs, as well as HAEC binding by monocytes and PMNs, in a concentration-dependent manner; increases total 5-lipoxygenase metabolites in murine RPMs at 37.5 µM; induces apoptosis in A7r5 rat aortic smooth muscle cells in vitro at 50 µM; levels are increased in the serum, LDL, and PBMCs of patients with coronary artery disease; UVA irradiation increases PGPC levels in cultured human skin fibroblasts |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1-Hexadecanoyl-2-glutaroyl-sn-glycero-3-phosphocholine|1-Palmitoyl-2-glutaryl phosphatidylcholine|1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine |
Gene, Accession, CAS # | CAS: 89947-79-5 |
Catalog # | 10044-10 |
Price | |
Order / More Info | PGPC from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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