产品详情 |
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Antigenic Specificity | mTOR |
Clone | F11 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, kappa |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1-5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | mTOR Monoclonal Antibody (F11), eBioscience™. Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation. Mutations affecting the gene results in Smith-Kingsmore syndrome. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 2475, 56717; Uniprot: P42345, Q9JLN9 |
Catalog # | 14-2190-80 |
Price | |
Order / More Info | mTOR Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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