产品详情 |
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Antigenic Specificity | CD184 (CXCR4) |
Clone | 12G5 |
Host Species | Mouse |
Reactive Species | human, African green, baboon, chimpanzee, cynomolgus, rhesus, sooty mangabey |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), Immunofluorescence Microscopy (IF), CyTOF®, ICC, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-human CD184 (CXCR4). CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2. |
Immunogen | CP-MAC-infected Sup-T1 cells |
Other Names | CXCR4, Fusin |
Gene, Accession # | Gene ID: 7852 |
Catalog # | 306502 |
Price | |
Order / More Info | CD184 (CXCR4) Antibody from BIOLEGEND |
Product Specific References | n/a |
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