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| Product Name | MGL-3196 |
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| Description | An agonist of TRβ (EC50s = 0.21 and 3.74 µM for TRβ and TRα, respectively); inhibits hERG channels (IC50 = 30 µM); liver-directed, with a liver to plasma ratio of 8:1 to reduce systemic exposure; does not affect the expression of α-MHC in a rat model of hypothyroidism, an effect mediated by TRα; lowers non-HDL cholesterol and liver triglycerides without affecting Tsh levels in rat and rabbit models of hypercholesterolemia; lowers plasma glucose levels and improves insulin sensitivity in DIO mice |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MGL3196 VIA3196 TRa TRb aMHC VIA-3196 αMHC high density lipoprotein nonalcoholic |
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| Gene, Accession, CAS # | CAS: 920509-32-6 |
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| Catalog # | 23845-1 |
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| Order / More Info | MGL-3196 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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