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| Antigenic Specificity | STAT6 (pT645) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | IHC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | STAT6 (pT645) Antibody is a Rabbit Polyclonal antibody against STAT6 (pT645). The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants. |
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| Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding T645 of human STAT6. |
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| Other Names | 12S1644; IL-4 Stat; IL-4-STAT; Signal transducer and activator of transcription 6; interleukin-4 induced; STAT; interleukin4-induced; STAT6; STAT6B; STAT6C; transcription factor IL-4 STAT; D12S1644; Signal Transducer And Activator Of Transcription 6,Interleukin-4 Induced |
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| Gene, Accession # | STAT6, Gene ID: 6778, SwissProt: P42226 |
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| Catalog # | abx000502 |
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| Price | |
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| Order / More Info | STAT6 (pT645) Antibody from ABBEXA |
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| Product Specific References | n/a |
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