| 产品详情 |
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| Product Name | MG624 |
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| Description | An antagonist of neuronal nicotinic AChRs (Ki = 0.055 µM); selective for neuronal nAChRs over muscle-type AChRs (Ki = 70 µM); inhibits acetylcholine-evoked currents in Xenopus oocytes expressing chick α7 subunit-containing nAChRs (IC50 = 95 nM); selective for α7 subunit-containing nAChRs over α6, β2, and β4 subunit-containing nAChRs (Kis = 4.52, 12, and 9.2 µM, respectively); decreases vagus nerve stimulation-induced contractions of isolated guinea pig vagus nerve-stomach preparations (EC50 = 49.4 µM); decreases Egr-1 protein levels in and proliferation of HMEC-Ls; decreases angiogenesis in vitro, ex vivo, and in an H69 SCLC mouse xenograft model at approximately 10 mg/kg per day as well as reduces tumor growth in the H69 SCLC mouse xenograft model |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 778527-06-3 MG-624 Stilonium TE-671 Egr1 HMECLs H-69 |
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| Gene, Accession, CAS # | CAS: 77257-42-2 |
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| Catalog # | 24298-1 |
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| Price | |
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| Order / More Info | MG624 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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