产品名称 UBE2D1 Antibody from ABBEXA
产品货号 abx031522
产品价格 现货询价,电话:010-67529703
产品规格 80 µl, 400 µl
产品品牌 ABBEXA
产品概述
产品详情
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Antigenic SpecificityUBE2D1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpurified
Size80 µl, 400 µl
Concentrationn/a
ApplicationsWB, IHC. RUO
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DescriptionThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. This UBE2D1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human UBE2D1.
ImmunogenHuman UBE2D1.
Other NamesUBE2D1; SFT; UBC5A; UBCH5; UBCH5A; Ubiquitin-conjugating enzyme E2 D1; Stimulator of Fe transport; UBC4/5 homolog; Ubiquitin carrier protein D1; Ubiquitin-conjugating enzyme E2 (17) KB 1; Ubiquitin-conjugating enzyme E2-17 kDa 1; Ubiquitin-protein ligase D1; UBC4/5; E2 (17)KB1; Ubiquitin-conjugating enzyme E2(17)KB 1
Gene, Accession #SwissProt: P51668
Catalog #abx031522
Price
Order / More InfoUBE2D1 Antibody from ABBEXA
Product Specific Referencesn/a
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