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| Product Name | Indoxyl Sulfate (potassium salt) |
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| Description | A metabolite of tryptophan derived from dietary protein that can accumulate to toxic levels in instances of uremia; 250 µM can induce the activation of NF-κB, promoting the expression of both TGF-β1 and Smad3 expression in proximal tubular cells of rats, which is associated with profibrotic activity, |
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| Size | 1 g |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | uremia chronic kidney disease metabolite protein metabolism NF-κB TGF-β1 Smad3 biochemical NFκB TGFβ1 oxidative injury renal uremic toxin tryptophan indole intestinal bacteria absorbed blood liver stress disease progression induce activation promote expression profibrotic activity 487-94-5 1309597-66-7 Potassium indol-3-yl sulfate Potassiumindol-3-ylsulfate |
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| Gene, Accession, CAS # | CAS: 2642-37-7 |
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| Catalog # | 16926-1 |
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| Order / More Info | Indoxyl Sulfate (potassium salt) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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