产品详情 |
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Antigenic Specificity | Nesprin 1 |
Clone | OTI1E10 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:500, Western Blot: 1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nesprin 1 Monoclonal Antibody (OTI1E10). There are two genes encoding members of a new family of type II integral membrane proteins. Both are ubiquitously expressed, and tissue-specific alternative mRNA initiation and splicing generate at least two major isoforms of each protein, with the smaller isoforms being truncated at the N-terminus. These proteins are called nesprin-l and -2 for nuclear _envelope _spectrin repeat, as they are characterized by the presence of multiple, clustered spectrin repeats, bipartite nuclear localization sequences and a conserved C-terminal, single transmembrane domain. Transient transfection of EGFP-fusion expression constructs demonstrated their localization to the nuclear membrane with a novel C-terminal, TM- |
Immunogen | n/a |
Other Names | SYNE 1; RP1-130E4.2; 8B; ARCA1; C6orf98; CPG2; DKFZp781J13156; EDMD4; FLJ30878; FLJ41140; KIAA0796; KIAA1262; KIAA1756; MYNE1; SCAR8; dJ45H2.2; Enaptin; Myocyte nuclear envelope protein 1; Myne-1; Nuclear envelope spectrin repeat protein 1; Synaptic nuclear envelope protein 1 |
Gene, Accession # | Entrez: 23345; Uniprot: Q8NF91 |
Catalog # | MA5-27519 |
Price | |
Order / More Info | Nesprin 1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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