| 产品详情 |
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| Antigenic Specificity | Nesprin 1 |
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| Clone | MANNES1A(7A12) |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rabbit, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:200, Immunofluorescence: 1:200, Western Blot: 1:400-1:800 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Nesprin 1 Monoclonal Antibody (MANNES1A(7A12)). There are two genes encoding members of a new family of type II integral membrane proteins. Both are ubiquitously expressed, and tissue-specific alternative mRNA initiation and splicing generate at least two major isoforms of each protein, with the smaller isoforms being truncated at the N-terminus. These proteins are called nesprin-l and -2 for nuclear _envelope _spectrin repeat, as they are characterized by the presence of multiple, clustered spectrin repeats, bipartite nuclear localization sequences and a conserved C-terminal, single transmembrane domain. Transient transfection of EGFP-fusion expression constructs demonstrated their localization to the nuclear membrane with a novel C-termin |
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| Immunogen | n/a |
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| Other Names | SYNE 1; RP1-130E4.2; 8B; ARCA1; C6orf98; CPG2; DKFZp781J13156; EDMD4; FLJ30878; FLJ41140; KIAA0796; KIAA1262; KIAA1756; MYNE1; SCAR8; dJ45H2.2; Enaptin; Myocyte nuclear envelope protein 1; Myne-1; Nuclear envelope spectrin repeat protein 1; Synaptic nuclear envelope protein 1 |
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| Gene, Accession # | Entrez: 100347993, 23345, 499010, 64009; Uniprot: Q6ZWR6, Q8NF91 |
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| Catalog # | MA5-18077 |
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| Price | |
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| Order / More Info | Nesprin 1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 27697922 |
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