| 产品详情 |
| Edit |   |
|---|
| Product Name | ND-630 |
|---|
| Description | An inhibitor of ACC1 and ACC2 (IC50s = 2.1 and 6.1 nM, respectively, for the human enzymes); inhibits ACC dimerization; selective for ACC over 101 enzymes, receptors, growth factors, transporters, and ion channels up to a concentration of 10 µM; reduces fatty acid synthesis in HepG2 cells (EC50s = 66 and 9 nM in 10% FBS and serum-free media, respectively); reduces hepatic steatosis, improves glucose-stimulated insulin secretion, and reduces hemoglobin A1c levels by 0.9% in Zucker diabetic rats |
|---|
| Size | 5 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | ND630 NDI010976 NDI-010976 ACC-1 2 Hep-G2 FA |
|---|
| Gene, Accession, CAS # | CAS: 1434635-54-7 |
|---|
| Catalog # | 23961-5 |
|---|
| Price | |
|---|
| Order / More Info | ND-630 from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|