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| Product Name | 5,7-Dichlorokynurenic Acid |
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| Description | An NMDA receptor antagonist (Ki = 40 nM in a radioligand binding assay); selectively selectively inhibits glycine- over kainate-induced NDMA currents at 15 µM in Xenopus oocytes expressing rat NMDA receptors; reduces NMDA-induced neurotoxicity in primary rat cortical neurons from 1 to 10 µM; reverses mechanical hyperalgesia in magnesium-deficient rats in a dose-dependent manner from 0.97-97 nmol; blocks the positive ionotropic effect, hypertension, and increase in myocardial oxygen demand induced by electrical stimulation of the PVN in anesthetized rabbits; increases social interaction time and time spent in the open arms of the elevated plus maze; disinhibits conflict responding in the Cook and Davidson conditioned conflict paradigm |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5,7-DCKA|DCKA |
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| Gene, Accession, CAS # | CAS: 131123-76-7 |
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| Catalog # | 25533-25 |
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| Order / More Info | 5,7-Dichlorokynurenic Acid from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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