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Product Name | Thiocarlide |
Description | Isoxyl is a thiourea derivative that was used in the 1960s to successfully treat tuberculosis (TB). It has considerable antimycobacterial activity in vitro and is effective against multi-drug resistant strains of Mycobacterium tuberculosis in the range of 1-10 µg/ml.{13370,13371} At concentrations of 10 µM, isoxyl inhibits the synthesis of M. bovis during six hours of exposure which is similar to isoniazid (INH) and ethionamide (ETH), two other predominant anti-TB drugs. Unlike INH and ETH, isoxyl also partially inhibits the synthesis of fatty acids. Isoxyl shows no acute toxicity against primary macrophage cell cultures as demonstrated by diminution of redox activity.{13371} |
Size | 500 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Isoxyl |
Gene, Accession, CAS # | CAS: 910-86-1 |
Catalog # | 10006976-500 |
Price | |
Order / More Info | Thiocarlide from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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