| 产品详情 |
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| Antigenic Specificity | AIM |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 10 µg/mL, Western Blot: 0.5-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | AIM Polyclonal Antibody. Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. AIM was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant AIM significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense |
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| Immunogen | n/a |
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| Other Names | UNQ203/PRO229, AIM, API6, PRO229, SP-ALPHA, Spalpha; CD5 antigen-like; CD5 antigen-like (scavenger receptor cysteine rich family); CT-2; apoptosis inhibitor 6; igM-associated peptide |
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| Gene, Accession # | Entrez: 11801, 922; Uniprot: O43866, Q9QWK4 |
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| Catalog # | PA5-20242 |
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| Price | |
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| Order / More Info | AIM Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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