产品详情 |
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Antigenic Specificity | AIM |
Clone | 11H48L16 |
Host Species | Recombinant Rabbit |
Reactive Species | mouse |
Isotype | IgG |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100, Immunofluorescence: 1:100 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | AIM Antibody (11H48L16), ABfinity™ Rabbit Monoclonal. Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. AIM is a secreted protein that acts as a key regulator of lipid synthesis. It is mainly expressed in macrophages in lymphoid and inflamed tissues and regulates mechanisms in inflammatory responses - such as infection or atherosclerosis. AIM is able to inhibit lipid droplet size in adipocytes. Following incorporation into mature adipocytes via CD36-mediated endocytosis AIM associates with cytosolic FASN and inhibits fatty acid synthase activity and leads to lipolysis - the degradation of triacylglyc |
Immunogen | n/a |
Other Names | AIM, API6, CD5L |
Gene, Accession # | Entrez: 11801; Uniprot: Q9QWK4 |
Catalog # | 703558 |
Price | |
Order / More Info | AIM Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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