产品详情 |
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Product Name | Dp44mT |
Description | An iron chelator with antiproliferative effects; inhibits in vitro proliferation of SK-N-MC neuroepithelioma, SK-Mel-28 melanoma, and MCF-7 breast cancer cells (IC50s = 30, 60, and 60 nM, respectively); increases mobilization of 59Fe from SK-N-MC cells and M109 mouse lung carcinoma cells (25 and 1 µM, respectively); enhances cytotoxicity in several multidrug resistant human cancer cell lines following transport to lysosomes by P-glycoprotein; inhibits M109 tumor growth in mice, reducing tumor weight to 47% of control values (0.4 mg/kg); reduces tumor size and weight in an oral squamous cell carcinoma mouse xenograft model (0.5 mg/kg), |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | anti-proliferative SKNMC SKMel28 MCF7 MRC5 M-109 NDRG-1 DU-145 59-Fe PC-3 |
Gene, Accession, CAS # | CAS: 152095-12-0 |
Catalog # | 20936-50 |
Price | |
Order / More Info | Dp44mT from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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