产品名称 Dp44mT from CAYMAN CHEMICAL COMPANY
产品货号 20936-50
产品价格 现货询价,电话:010-67529703
产品规格 50 mg
产品品牌 CAYMAN CHEMICAL COMPANY
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Product NameDp44mT
DescriptionAn iron chelator with antiproliferative effects; inhibits in vitro proliferation of SK-N-MC neuroepithelioma, SK-Mel-28 melanoma, and MCF-7 breast cancer cells (IC50s = 30, 60, and 60 nM, respectively); increases mobilization of 59Fe from SK-N-MC cells and M109 mouse lung carcinoma cells (25 and 1 µM, respectively); enhances cytotoxicity in several multidrug resistant human cancer cell lines following transport to lysosomes by P-glycoprotein; inhibits M109 tumor growth in mice, reducing tumor weight to 47% of control values (0.4 mg/kg); reduces tumor size and weight in an oral squamous cell carcinoma mouse xenograft model (0.5 mg/kg),
Size50 mg
Concentrationn/a
Applicationsn/a
Other Namesanti-proliferative SKNMC SKMel28 MCF7 MRC5 M-109 NDRG-1 DU-145 59-Fe PC-3
Gene, Accession, CAS #CAS: 152095-12-0
Catalog #20936-50
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Order / More InfoDp44mT from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
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