| 产品详情 |
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| Product Name | CHIR124 |
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| Description | A selective, cell-permeable, quinolone-based inhibitor of Chk1 (IC50 = 0.3 nM versus 0.7 µM for Chk1 and Chk2, respectively); inhibits p53-mutant solid tumor cell growth in synergy with topoisomerase I poisons or ionizing radiation, potentiating tumor apoptosis |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | checkpoint 1 kinase inhibitor Chk1 topoisomerases I radiosensitizations p53 cells cycles antitumor anti-tumor apoptosis cancer DNA damage repair biochemical selective CHIR-124 permeable quinolone-based in vitro selective selectivity inhibit poison ionizing radiations growth mutant solid tumor xenograft model potentiate |
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| Gene, Accession, CAS # | CAS: 405168-58-3 |
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| Catalog # | 16553-1 |
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| Price | |
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| Order / More Info | CHIR124 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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