产品详情 |
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Antigenic Specificity | MCM2 |
Clone | 2B3 |
Host Species | Mouse |
Reactive Species | human, mouse, nonhuman primate, rat |
Isotype | IgG1 |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Flow Cytometry: 1/200 - 1/400, Immunohistochemistry: 1/200 - 1/1000, Western Blot: 1/500 - 1/2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MCM2 Monoclonal Antibody (2B3). The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. |
Immunogen | n/a |
Other Names | BM28, CCNL1, CDCL1, D3S3194, MITOTIN, cdc19, DNA replication licensing factor MCM2; MCM2 minichromosome maintenance deficient 2, mitotin; cell devision cycle-like 1; cyclin-like 1; minichromosome maintenance deficient 2 (mitotin); minichromosome maintenance protein 2 homolog; nuclear protein BM28 |
Gene, Accession # | Entrez: 17216, 312538, 4171; Uniprot: P49736, P97310 |
Catalog # | MA5-15895 |
Price | |
Order / More Info | MCM2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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