产品详情 |
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Antigenic Specificity | AXIN1 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunohistochemistry: 3-5 µg/mL, peptide-ELISA: 1:128000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | AXIN1 Polyclonal Antibody. This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling domain and a dishevelled and axin domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants enc |
Immunogen | n/a |
Other Names | AXIN1; axin 1; AXIN; LA16c-314G4.3; MGC52315; axis inhibition protein 1; axis inhibitor 1; fused, mouse, homolog of |
Gene, Accession # | Entrez: 8312; Uniprot: O15169 |
Catalog # | PA5-18024 |
Price | |
Order / More Info | AXIN1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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